17 research outputs found

    Evaluation Methods for Rankings of Facetvalues for Faceted Search

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    Abstract. We introduce two metrics aimed at evaluating systems that select facetvalues for a faceted search interface. Facetvalues are the values of meta-data fields in semi-structured data and are commonly used to refine queries. It is often the case that there are more facetvalues than can be displayed to a user and thus a selection has to be made. Our metrics evaluate these selections based on binary relevant assessments for the documents in a collection. Both our metrics are based on Normalized Discounted Cumulated Gain, an often used Information Retrieval metric.

    Exploratory Web Searching with Dynamic Taxonomies and Results Clustering

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    Abstract. This paper proposes exploiting both explicit and mined metadata for enriching Web searching with exploration services. On-line results clustering is useful for providing users with overviews of the results and thus allowing them to restrict their focus to the desired parts. On the other hand, the various metadata that are available to a WSE (Web Search Engine), e.g. domain/language/date/filetype, are commonly exploited only through the advanced (form-based) search facilities that some WSEs offer (and users rarely use). We propose an approach that combines both kinds of metadata by adopting the interaction paradigm of dynamic taxonomies and faceted exploration. This combination results to an effective, flexible and efficient exploration experience.

    Milk and serum proteomes in subclinical and clinical mastitis in Simmental cows

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    Bovine mastitis causes changes in the milk and serum proteomes. Here changes in both proteomes caused by naturally occurring subclinical and clinical mastitis have been characterised and quantified. Milk and serum samples from healthy dairy cows (n = 10) were compared to those of cows with subclinical (n = 12) and clinical mastitis (n = 10) using tandem mass tag (TMT) proteomics. Proteins that significantly increased or decreased in milk (n = 237) or serum (n = 117) were quantified and classified by the type of change in subclinical and clinical mastitis. A group of the proteins (n = 38) showed changes in both milk and serum a number of which decreased in the serum but increased in milk, suggesting a particular role in host defence for maintaining and restoring homeostasis during the disease. Proteins affected by bovine mastitis included proteins in host defence and coagulation pathways. Investigation of the modified proteomes in milk and serum was assessed by assays for haptoglobin, serum amyloid A and α acid glycoprotein validating the results obtained by quantitative proteomics. Alteration of abundance patterns of milk and serum proteins, together with pathway analysis reveal multiple interactions related to proteins affected by mastitis. Data are available via ProteomeXchange with identifier PXD022595. SIGNIFICANCE: Mastitis is the most serious condition to affect dairy cows and leads to reduced animal welfare as well as having a negative economic effect for the dairy industry. Proteomics has previously identified changes in abundance of milk proteins during mastitis, but there have been few investigations addressing changes that may affect proteins in the blood during the infection. In this study, changes in the abundance of proteins of milk and serum, caused by naturally occurring mastitis have been characterised by proteomics using a quantitative approach and both subclinical and clinical cases of mastitis have been investigated. In both milk and serum, change in individual proteins was determined and classified into varying types of altering abundance, such as increasing in subclinical mastitis, but showing no further increase in clinical mastitis. Of special interest were the proteins that altered in abundance in both milk and serum which either showed similar trends - increasing or decreasing in both biological fluids or showed reciprocal change decreasing in serum but increasing in milk. As well as characterising proteins as potential markers of mastitis and the severity of the disease, these results provide insight into the pathophysiology of the host response to bovine mastitis

    Creativity support tools: Report from a U.S. National Science Foundation sponsored workshop

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    Creativity support tools is a research topic with high risk but potentially very high payoff. The goal is to develop improved software and user interfaces that empower users to be not only more productive but also more innovative. Potential users include software and other engineers, diverse scientists, product and graphic designers, architects, educators, students, and many others. Enhanced interfaces could enable more effective searching of intellectual resources, improved collaboration among teams, and more rapid discovery processes. These advanced interfaces should also provide potent support in hypothesis formation, speedier evaluation of alternatives, improved understanding through visualization, and better dissemination of results. For creative endeavors that require composition of novel artifacts (e.g., computer programs, scientific papers, engineering diagrams, symphonies, artwork), enhanced interfaces could facilitate exploration of alternatives, prevent unproductive choices, and enable easy backtracking. This U.S. National Science Foundation sponsored workshop brought together 25 research leaders and graduate students to share experiences, identify opportunities, and formulate research challenges. Two key outcomes emerged: (a) encouragement to evaluate creativity support tools through multidimensional in-depth longitudinal case studies and (b) formulation of 12 principles for design of creativity support tools. Copyright © 2006, Lawrence Erlbaum Associates, Inc
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